Can LOTRONEX® help improve control of bowel urgency?
Fewer “now means now” moments with LOTRONEX
Bowel urgency is a term that doctors use to describe the feeling of needing to go immediately. Women suffering from bowel urgency may do some of the following:
- Keep a change of clothes in the car in case of accidents
- Map out bathrooms before leaving the house
- Stay home to be close to the bathroom
A 12-week study was done to see how well LOTRONEX improved control of bowel urgency*

At week 12, women reported 6 out of 7 days with satisfactory control, versus 5 out of 7 with sugar pills.* *In this study, 532 women took Lotronex and 269 took sugar pills.
What can LOTRONEX® do about stomach pain and discomfort?
LOTRONEX may help relieve stomach pain and discomfort
Painful stomach cramps can be one of the most unpleasant symptoms of IBS with diarrhea. If you’ve tried treating your symptoms and are still suffering, it may be time to consider LOTRONEX, which works differently from other medicines.
Can LOTRONEX® reduce the frequency of diarrhea?
LOTRONEX is proven to reduce the frequency of bowel movements for some women
Does it seem like you’re in and out of the bathroom all day sometimes? Unlike bowel urgency, which describes a feeling, the frequency of bowel movements means the number of times you go in a day. LOTRONEX is proven to lower the number of bathroom trips for some women.

IBS is about one-and-a-half times more common in women than in men.* Three in ten with IBS have diarrhea.* One in four cases is considered severe.*
*In this 12-week study, 177 women took LOTRONEX and 176 took placebo.
LOTRONEX may also give some women less diarrhea and more firm bowel movements.
Can LOTRONEX® help me get back to the things that matter most to me?
Women taking LOTRONEX may report less interference with these specific daily activities
No matter which specific symptoms you are suffering from, IBS with diarrhea often gets in the way of normal daily activities. If you feel like you are missing work or skipping social events, it may be time to talk to your doctor about LOTRONEX.
In a review of two 12-week studies, women taking LOTRONEX reported:

Women who took LOTRONEX, when compared with women taking sugar pills, did not report additional benefits in their IBS symptoms with regard to emotional and mental problems and physical and sexual activity.